From molecular sequence to informed peptide design
The sequence of a peptide determines much of its structural behaviour, interactions and functional properties. Designing an effective peptide therefore requires more than selecting amino acids. It involves understanding how sequence composition, charge, hydrophobicity, conformation and molecular interactions influence performance.
At Peptide Intelligence Consulting, we combine peptide chemistry, supramolecular science and computational approaches to help researchers and R&D teams make informed decisions about peptide design, modification and optimization.
Our goal is to translate scientific questions into clear design strategies and practical experimental directions.
Our capabilities
Develop and assess peptide sequences using molecular design principles, physicochemical properties and the intended application.
Evaluate sequence variants and identify how amino acid substitutions and sequence changes may influence peptide behaviour and function.
Investigate peptide–membrane interactions, amphipathic structures, membrane selectivity and strategies for tuning membrane activity.
Explore chemical modifications, cyclization, stapling and other design strategies to tune peptide stability, solubility, conformation and function.
Use appropriate computational methods to investigate peptide structures, compare candidate sequences and support experimental prioritization.
Our approach
Understand → Analyse → Design → Evaluate
We begin by defining the scientific question and the desired peptide properties. We then assess relevant sequence and structural features, develop design hypotheses, and recommend suitable computational or experimental approaches for evaluating candidate peptides.
The workflow is tailored to the scientific objective, available data and project stage.
Whether you are developing a new peptide sequence, optimizing an existing candidate or investigating peptide interactions, we can help you define the next steps.